Tmc7^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmc7^em1(IMPC)Mbp
• Name: transmembrane channel-like gene family 7; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:6152662
• Gene: Tmc7 Location: Chr7:118135064-118183959 bp, - strand Genetic Position: Chr7, 63.44 cM
• Alliance: Tmc7^em1(IMPC)Mbp page
• IMPC: Tmc7 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at UC Davis by injecting CAS9 RNA and 4 guide sequences CCCCCAGGTCTTGCCTACAACCC, GGTGTGTGATATGCAGCCTGGGG, GCTGGACAGCAGCATTTAAGTGG, CCAGATAGTCTAGCTGACCAGCT, which resulted in a Exon Deletion. (J:237616)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tmc7 Mutation: 41 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)