Paics^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Paics^em1(IMPC)Mbp
• Name: phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:6152730
• Gene: Paics Location: Chr5:77099154-77115356 bp, + strand Genetic Position: Chr5, 41.45 cM, cytoband E1
• Alliance: Paics^em1(IMPC)Mbp page
• IMPC: Paics gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at UC Davis by injecting CAS9 Protein and 4 guide sequences CCCACTACCATTACAGCTAGCCT, CCACCTGACCGGAGCTCTCATCC, AGGGTGGTGTGAAGAGGCCCAGG, CCCTGTGTGCTTAGACTACAAAC, which resulted in a Exon Deletion. (J:237616)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Paics Mutation: 35 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 4 reference(s)