Syt7^em2(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Syt7^em2(IMPC)H
• Name: synaptotagmin VII; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:6153890
• Gene: Syt7 Location: Chr19:10366454-10430544 bp, + strand Genetic Position: Chr19, 6.58 cM, cytoband B
• Alliance: Syt7^em2(IMPC)H page
• IMPC: Syt7 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 RNA, 3 guide sequences CCTGTAAACTATATCATCCACGG, GGGGGAGACTGTTACAGGCTAGG, TTGAGGGGGGAGACTGTTACAGG, and a donor oligo, which resulted in a Exon Deletion. (J:237616)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Syt7 Mutation: 41 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 4 reference(s)