Trip11^tm1.2Psmi
Targeted Allele Detail

Summary

• Symbol: Trip11^tm1.2Psmi
• Name: thyroid hormone receptor interactor 11; targeted mutation 1.2, Patrick Smits
• MGI ID: MGI:6154133
• Synonyms: Trip11^-
• Gene: Trip11 Location: Chr12:101800304-101879463 bp, - strand Genetic Position: Chr12, 51.3 cM, cytoband F1
• Alliance: Trip11^tm1.2Psmi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:253969
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Cre excision of the loxP-flanked exon 1 results in this null allele. (J:253969)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trip11 Mutation: 99 strains or lines available

References

• Original: J:253969 Bird IM, et al., The skeletal phenotype of achondrogenesis type 1A is caused exclusively by cartilage defects. Development. 2018 Jan 8;145(1):dev156588
• All: 1 reference(s)