About   Help   FAQ
Lhfpl4tm1Lex
Targeted Allele Detail
Summary
Symbol: Lhfpl4tm1Lex
Name: lipoma HMGIC fusion partner-like protein 4; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:6154882
Synonyms: Lhfpl4-
Gene: Lhfpl4  Location: Chr6:113145051-113172345 bp, - strand  Genetic Position: Chr6, 52.74 cM
Alliance: Lhfpl4tm1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:254795
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 and 2 (the latter containing the ATG translation start site) and intervening intron 1, were replaced with sequence containing a lacZ reporter cassette and a LoxP site flanked puromycin resistance gene cassette. (J:254795)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lhfpl4 Mutation:  12 strains or lines available
Notes
Taconic mouse line TF4076.
References
Original:  J:254795 Davenport EC, et al., An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors. Cell Rep. 2017 Oct 3;21(1):70-83
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory