Magt1^{Gt(IST13422E1)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Magt1^{Gt(IST13422E1)Tigm}
• Name: magnesium transporter 1; gene trap IST13422E1, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:6155597
• Gene: Magt1 Location: ChrX:105011690-105055408 bp, - strand Genetic Position: ChrX, 47.36 cM
• Alliance: Magt1^{Gt(IST13422E1)Tigm} page

Mutation origin

• Mutant Cell Line: IST13422E1
• Germline Transmission: Earliest citation of germline transmission: J:260923
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Trapped gene association determined by genome coordinate overlap and strand. (J:260923)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Magt1 Mutation: 22 strains or lines available

References

• Original: J:260923 Gotru SK, et al., Cutting Edge: Imbalanced Cation Homeostasis in MAGT1-Deficient B Cells Dysregulates B Cell Development and Signaling in Mice. J Immunol. 2018 Apr 15;200(8):2529-2534
• All: 1 reference(s)