Atp2c2^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atp2c2^em1(IMPC)Tcp
• Name: ATPase, Ca++ transporting, type 2C, member 2; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:6156482
• Gene: Atp2c2 Location: Chr8:120426748-120484456 bp, + strand Genetic Position: Chr8, 68.21 cM, cytoband E1
• Alliance: Atp2c2^em1(IMPC)Tcp page
• IMPC: Atp2c2 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from project TCPR0756 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of TGGTCACCTATAACTGTC and GCAGTAGCCTCGTTTCTC targeting the 5' side and TAGTTTGTCCTGACGAGC and TGACCATGGGTAACAATC targeting the 3' side of exon ENSMUSE00000605799 resulting in a 857-bp deletion of Chr8 from 119729576 to 119730432_insTTGGA (GRCm38). (J:237616)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Atp2c2 Mutation: 49 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)