Gars1^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gars1^em1(IMPC)Tcp
• Name: glycyl-tRNA synthetase 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:6156586
• Gene: Gars1 Location: Chr6:55014992-55056485 bp, + strand Genetic Position: Chr6, 27.29 cM
• Alliance: Gars1^em1(IMPC)Tcp page
• IMPC: Gars1 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from project TCPR0862 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GCTCCCTCTACTCACTGAAA and GTAACGCTCTTTGGCGCAGA targeting the 5' side and GGTTAGCTATTAACTTGTAA and ATATACCTGCTGCTCACAGG targeting the 3' side leading to a 409-bp deletion from Chr6:55050182 to 55050590 (GRCm38). (J:237616)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Gars1 Mutation: 42 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 3 reference(s)