Armc5^tm1Stra
Targeted Allele Detail

Summary

• Symbol: Armc5^tm1Stra
• Name: armadillo repeat containing 5; targeted mutation 1, Constantine A Stratakis
• MGI ID: MGI:6157645
• Gene: Armc5 Location: Chr7:127836514-127844272 bp, + strand Genetic Position: Chr7, 70.06 cM
• Alliance: Armc5^tm1Stra page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:244906
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout)
• Mutation: Insertion
• Mutation details: The EUCOMM targeting vector introduced into intron 1 an FRT site, lacZ reporter gene, loxP site, neomycin resistance cassette, FRT site, and loxP site. An addiional loxP site was inserted downstream of exon 3. (J:244906)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Armc5 Mutation: 17 strains or lines available

References

• Original: J:244906 Berthon A, et al., Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function. Hum Mol Genet. 2017 Sep 15;26(18):3495-3507
• All: 1 reference(s)