Igsf8^tm1.1Osb
Targeted Allele Detail

Summary

• Symbol: Igsf8^tm1.1Osb
• Name: immunoglobulin superfamily, member 8; targeted mutation 1.1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6157960
• Synonyms: Igsf8^F
• Gene: Igsf8 Location: Chr1:172139934-172147410 bp, + strand Genetic Position: Chr1, 79.59 cM
• Alliance: Igsf8^tm1.1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260669
• Parent Cell Line: EGR-05 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A Neomycin resistance gene cassette (flanked by FRT sites) was inserted between exons 2 and 3. The first and second loxP sites were inserted upstream of the neomycin selection cassette and downstream of exon 5, respectively. The neomycin selection cassete was removed via flp-mediated recombination. (J:260669)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Igsf8 Mutation: 26 strains or lines available

References

• Original: J:260669 Inoue N, et al., Tetraspanin-interacting protein IGSF8 is dispensable for mouse fertility. Fertil Steril. 2012 Aug;98(2):465-70
• All: 3 reference(s)