Igsf8^tm1.2Osb
Targeted Allele Detail

Summary

• Symbol: Igsf8^tm1.2Osb
• Name: immunoglobulin superfamily, member 8; targeted mutation 1.2, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6157961
• Synonyms: Igsf8^-
• Gene: Igsf8 Location: Chr1:172139934-172147410 bp, + strand Genetic Position: Chr1, 79.59 cM
• Alliance: Igsf8^tm1.2Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260669
• Parent Cell Line: EGR-05 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 3-5 were deleted. Western blot analysis confirmed the absence of protein expression in egg lysates from homozygous mutant female mice. (J:260669)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igsf8 Mutation: 26 strains or lines available

References

• Original: J:260669 Inoue N, et al., Tetraspanin-interacting protein IGSF8 is dispensable for mouse fertility. Fertil Steril. 2012 Aug;98(2):465-70
• All: 1 reference(s)