Atg13^em1Nmz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atg13^em1Nmz
• Name: autophagy related 13; endonuclease-mediated mutation 1, Noboru Mizushima
• MGI ID: MGI:6158453
• Gene: Atg13 Location: Chr2:91504963-91540921 bp, - strand Genetic Position: Chr2, 50.63 cM
• Alliance: Atg13^em1Nmz page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Single point mutation
• Mutation details: CRISPR/Cas9 mutagenesis was used to introduce a a 1 bp insertion of a G resulting in a frameshift mutation in exon 5 of the gene. (J:236139)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Atg13 Mutation: 135 strains or lines available

References

• Original: J:236139 Kaizuka T, et al., Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol Cell Biol. 2015 Dec 07;36(4):585-95
• All: 1 reference(s)