Slc30a10^tm1Sommu
Targeted Allele Detail

Summary

• Symbol: Slc30a10^tm1Sommu
• Name: solute carrier family 30, member 10; targeted mutation 1, Somshuvra Mukhopadhyay
• MGI ID: MGI:6158650
• Synonyms: Slc30a10^flox
• Gene: Slc30a10 Location: Chr1:185187045-185200959 bp, + strand Genetic Position: Chr1, 89.53 cM
• Alliance: Slc30a10^tm1Sommu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:243657
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sites flanking exon 1 of the gene were inserted. (J:243657)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc30a10 Mutation: 20 strains or lines available

References

• Original: J:243657 Hutchens S, et al., Deficiency in the manganese efflux transporter SLC30A10 induces severe hypothyroidism in mice. J Biol Chem. 2017 Jun 09;292(23):9760-9773
• All: 2 reference(s)