Tmem59^tm1.1Tqw
Targeted Allele Detail

Summary

• Symbol: Tmem59^tm1.1Tqw
• Name: transmembrane protein 59; targeted mutation 1.1, Tieqiao Wen
• MGI ID: MGI:6158675
• Gene: Tmem59 Location: Chr4:107035827-107058193 bp, + strand Genetic Position: Chr4, 50.12 cM, cytoband C7
• Alliance: Tmem59^tm1.1Tqw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261729
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1 and a floxed neo cassette was inserted downstream of exon 1 via homologous recombination. Cre mediated recombination removed exon 1 and the neo cassette. (J:261729)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem59 Mutation: 26 strains or lines available

References

• Original: J:261729 Liu Q, et al., Dcf1 Triggers Dendritic Spine Formation and Facilitates Memory Acquisition. Mol Neurobiol. 2018 Jan;55(1):763-775
• All: 8 reference(s)