Cbln4^tm1.1Sud
Targeted Allele Detail

Summary

• Symbol: Cbln4^tm1.1Sud
• Name: cerebellin 4 precursor protein; targeted mutation 1.1, Thomas C Sudhof
• MGI ID: MGI:6160088
• Synonyms: Cbln4^F
• Gene: Cbln4 Location: Chr2:171878256-171885386 bp, - strand Genetic Position: Chr2, 94.74 cM
• Alliance: Cbln4^tm1.1Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260033
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an IRES-mVenus reporter, FRT flanked neo cassette loxP site, stop cassette and IRES-tdTomato reporter were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:260033)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cbln4 Mutation: 19 strains or lines available

References

• Original: J:260033 Seigneur E, et al., Cerebellins are differentially expressed in selective subsets of neurons throughout the brain. J Comp Neurol. 2017 Oct 15;525(15):3286-3311
• All: 7 reference(s)