Ftx^tm1.1Oka
Targeted Allele Detail

Summary

• Symbol: Ftx^tm1.1Oka
• Name: Ftx transcript, Xist regulator, non-protein coding; targeted mutation 1.1, Masaru Okabe
• MGI ID: MGI:6160397
• Gene: Ftx Location: ChrX:102604516-102667360 bp, - strand Genetic Position: ChrX, 46.21 cM
• Alliance: Ftx^tm1.1Oka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260691
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site replaced exons 1-4. Flp-mediated recombination removed the selection cassette. (J:260691)

Expression

In Mice Carrying this Mutation:	5 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ftx Mutation: 5 strains or lines available

References

• Original: J:260691 Soma M, et al., Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos. Sci Rep. 2014 Jun 5;4:5181
• All: 2 reference(s)