Tg(tetO-Sri)10Hhv
Transgene Detail

Summary

• Symbol: Tg(tetO-Sri)10Hhv
• Name: transgene insertion 10, Hector H Valdivia
• MGI ID: MGI:6160741
• Synonyms: SRI-tg10
• Transgene: Tg(tetO-Sri)10Hhv Location: unknown
• Alliance: Tg(tetO-Sri)10Hhv page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Sri)10Hhv expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sri (MGI:98419)

• Mutation details: A tetracycline responsive promoter drives inducible expression of the murine cDNA. Two lines were generated with 1 and 10 copies of the transgene, respectively. (J:246708)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:246708 Marmugi A, et al., Sorcin Links Pancreatic beta-Cell Lipotoxicity to ER Ca2+ Stores. Diabetes. 2016 Apr;65(4):1009-21
• All: 1 reference(s)