B3gnt7^tm1Akam
Targeted Allele Detail

Summary

• Symbol: B3gnt7^tm1Akam
• Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7; targeted mutation 1, Tomoya O Akama
• MGI ID: MGI:6160920
• Gene: B3gnt7 Location: Chr1:86230943-86235027 bp, + strand Genetic Position: Chr1, 43.94 cM
• Alliance: B3gnt7^tm1Akam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261660
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• An FRT-flanked neomycin resistance cassette was inserted downstream of a floxed exon 2. (J:261660)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any B3gnt7 Mutation: 37 strains or lines available

References

• Original: J:261660 Littlechild SL, et al., Keratan Sulfate Phenotype in the beta-1,3-N-Acetylglucosaminyltransferase-7-Null Mouse Cornea. Invest Ophthalmol Vis Sci. 2018 Mar 1;59(3):1641-1651
• All: 1 reference(s)