Ccdc136^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ccdc136^em1Smoc
• Name: coiled-coil domain containing 136; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6161253
• Synonyms: Ccdc136^-
• Gene: Ccdc136 Location: Chr6:29396296-29426954 bp, + strand Genetic Position: Chr6, 12.36 cM
• Alliance: Ccdc136^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exon 5 was disrupted by a 45bp deletion induced by CRISPR/Cas9 mutagenesis. (J:237643)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccdc136 Mutation: 33 strains or lines available

References

• Original: J:237643 Geng Q, et al., A Novel Testis-Specific Gene, Ccdc136, Is Required for Acrosome Formation and Fertilization in Mice. Reprod Sci. 2016 Oct;23(10):1387-96
• All: 1 reference(s)