Clmp^tm1.1Fgr
Targeted Allele Detail

Summary

• Symbol: Clmp^tm1.1Fgr
• Name: CXADR-like membrane protein; targeted mutation 1.1, Fritz G Rathjen
• MGI ID: MGI:6187882
• Synonyms: Clmp^tm1a.1/Fgr
• Gene: Clmp Location: Chr9:40597258-40696615 bp, + strand Genetic Position: Chr9, 21.42 cM
• Alliance: Clmp^tm1.1Fgr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258315
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a loxP-flanked neomycin cassette. Cre-mediated recombination removed the selection cassette. (J:258315)

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clmp Mutation: 203 strains or lines available

References

• Original: J:258315 Langhorst H, et al., The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice. Dis Model Mech. 2018 Feb 22;11(2):dmm032128
• All: 1 reference(s)