Spmip9^em1Qsh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spmip9^em1Qsh
• Name: sperm microtubule inner protein 9; endonuclease-mediated mutation 1, Qinghua Shi
• MGI ID: MGI:6188295
• Gene: Spmip9 Location: Chr6:70890071-70895911 bp, - strand Genetic Position: Chr6, 32.12 cM, cytoband C3
• Alliance: Spmip9^em1Qsh page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2J)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 mediated recombination produced a 44 bp deletion (c.58-102del) in exon 2. Western blot analysis confirmed the absence of protein expression in testes from homozygous mice. (J:263089)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spmip9 Mutation: 13 strains or lines available

References

• Original: J:263089 Khan M, et al., The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice. Sci Rep. 2018 Mar 21;8(1):4975
• All: 1 reference(s)