Lima1^tm1Blsg
Targeted Allele Detail

Summary

• Symbol: Lima1^tm1Blsg
• Name: LIM domain and actin binding 1; targeted mutation 1, Bao-Liang Song
• MGI ID: MGI:6192724
• Synonyms: Lima1^flox
• Gene: Lima1 Location: Chr15:99676351-99773292 bp, - strand Genetic Position: Chr15, 56.13 cM
• Alliance: Lima1^tm1Blsg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263730
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 5 was floxed. (J:263730)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lima1 Mutation: 83 strains or lines available

References

• Original: J:263730 Zhang YY, et al., A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption. Science. 2018 Jun 8;360(6393):1087-1092
• All: 1 reference(s)