Colgalt1^fosse
Chemically induced Allele Detail

Summary

• Symbol: Colgalt1^fosse
• Name: collagen beta(1-O)galactosyltransferase 1; fosse
• MGI ID: MGI:6194325
• Gene: Colgalt1 Location: Chr8:72063642-72077555 bp, + strand Genetic Position: Chr8, 34.43 cM
• Alliance: Colgalt1^fosse page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: The mutation substitutes an arginine for a highly conserved tryptophan in the nucleotide-diphospho-sugartransferase domain of the gene (c.T388C:p.W130R), which is in the N-terminal domain of the enzyme. (J:263533, J:277245)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Colgalt1 Mutation: 26 strains or lines available

References

• Original: J:263533 Geister KA, et al., Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice. G3 (Bethesda). 2018 Feb 2;8(2):401-409
• All: 2 reference(s)