Spmip6^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spmip6^em1Osb
• Name: sperm microtubule inner protein 6; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6194649
• Gene: Spmip6 Location: Chr4:41505009-41517333 bp, - strand Genetic Position: Chr4, 21.7 cM, cytoband B1
• Alliance: Spmip6^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR/Cas9 mediated recombination produced a 6bp deletion and 2bp insertion of an AT. (J:234235)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Spmip6 Mutation: 22 strains or lines available

References

• Original: J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10
• All: 1 reference(s)