Marchf11^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Marchf11^em1Osb
• Name: membrane associated ring-CH-type finger 11; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6194717
• Gene: Marchf11 Location: Chr15:26309134-26409662 bp, + strand Genetic Position: Chr15, 9.77 cM
• Alliance: Marchf11^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR/Cas9 mediated recombination produced a 54bp deletion and a 4bp insertion of an ATGA. (J:234235)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Marchf11 Mutation: 22 strains or lines available

References

• Original: J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10
• All: 1 reference(s)