Spaca7^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spaca7^em1Osb
• Name: sperm acrosome associated 7; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6194729
• Gene: Spaca7 Location: Chr8:12623038-12650744 bp, + strand Genetic Position: Chr8, 5.73 cM, cytoband A2
• Alliance: Spaca7^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 mediated recombination produced a 4bp deletion. (J:234235)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Spaca7 Mutation: 16 strains or lines available

References

• Original: J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10
• All: 1 reference(s)