Spink8^em2Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spink8^em2Osb
• Name: serine peptidase inhibitor, Kazal type 8; endonuclease-mediated mutation 2, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6194731
• Gene: Spink8 Location: Chr9:109641348-109655701 bp, + strand Genetic Position: Chr9, 59.77 cM
• Alliance: Spink8^em2Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 mediated recombination produced a 5bp deletion. (J:234235)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Spink8 Mutation: 10 strains or lines available

References

• Original: J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10
• All: 1 reference(s)