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Tmem86atm1b(KOMP)Mbp
Targeted Allele Detail
Summary
Symbol: Tmem86atm1b(KOMP)Mbp
Name: transmembrane protein 86A; targeted mutation 1b, Mouse Biology Program, UC Davis
MGI ID: MGI:6194941
Gene: Tmem86a  Location: Chr7:46700388-46704524 bp, + strand  Genetic Position: Chr7, 30.68 cM
Alliance: Tmem86atm1b(KOMP)Mbp page
IMPC: Tmem86a gene page
Mutation
origin
Mutant Cell Line:  DEPD00577_4_A11
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsCre-mediated excision of the parental Tmem86atm1a(KOMP)Mbp allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/aboutkompstrategies. (J:204739)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmem86a Mutation:  7 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory