Bcas3^tm1Msin
Targeted Allele Detail

Summary

• Symbol: Bcas3^tm1Msin
• Name: BCAS3 microtubule associated cell migration factor; targeted mutation 1, Maneesha S Inamdar
• MGI ID: MGI:6195662
• Synonyms: rudh^fl, rudh^flox, rudhira^flox
• Gene: Bcas3 Location: Chr11:85243993-85716884 bp, + strand Genetic Position: Chr11, 51.34 cM
• Alliance: Bcas3^tm1Msin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:262744
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 6. An additional loxP site was inserted downstream of exon 6. (J:262744)

Expression

In Mice Carrying this Mutation:	36 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcas3 Mutation: 76 strains or lines available

References

• Original: J:262744 Shetty R, et al., Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning. Sci Rep. 2018 Apr 4;8(1):5632
• All: 1 reference(s)