Scgb3a2^tm1.1Shk
Targeted Allele Detail

Summary

• Symbol: Scgb3a2^tm1.1Shk
• Name: secretoglobin, family 3A, member 2; targeted mutation 1.1, Shioko Kimura
• MGI ID: MGI:6196554
• Gene: Scgb3a2 Location: Chr18:43897354-43900464 bp, + strand Genetic Position: Chr18, 23.49 cM, cytoband C-D
• Alliance: Scgb3a2^tm1.1Shk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263506
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J x 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. A FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Cre-mediated recombination removed exons 2 through 3 and the selection cassette. (J:263506)

Expression

In Mice Carrying this Mutation:	7 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scgb3a2 Mutation: 13 strains or lines available

References

• Original: J:263506 Kido T, et al., Secretoglobin superfamily protein SCGB3A2 deficiency potentiates ovalbumin-induced allergic pulmonary inflammation. Mediators Inflamm. 2014;2014:216465
• All: 5 reference(s)