Vldlrm2Btlr
Chemically induced Allele Detail
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Symbol: |
Vldlrm2Btlr |
Name: |
very low density lipoprotein receptor; mutation 2, Bruce Beutler |
MGI ID: |
MGI:6197824 |
Synonyms: |
spotty |
Gene: |
Vldlr Location: Chr19:27193884-27231631 bp, + strand Genetic Position: Chr19, 21.77 cM
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Alliance: |
Vldlrm2Btlr page
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Strain of Origin: |
C57BL/6J
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Project Collection: |
Beutler Mutagenetix
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Allele Type: |
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Chemically induced (ENU) (Not Specified) |
Mutation: |
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Single point mutation
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Mutation details: ENU-induced T to C transition at base pair 27,238,792 (v38) on chromosome 19, or base pair 22,304 in the GenBank genomic region NC_000085 encoding Vldlr. The mutation corresponds to residue 1,607 in the mRNA sequence NM_013703 within exon 7 of 19 total exons, and residue 1,607 in the mRNA sequence NM_001161420 within exon 7 of 18 total exons. The mutation results in a cysteine (C) to arginine (R) substitution at position 338 (C338R) in both variants of the VLDLR protein.
(J:264645)
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Inheritance: |
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Recessive |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Vldlr Mutation: |
69 strains or lines available
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Original: |
J:264645 Ufret-Vincenty R, et al., Mutagenetix entry for spotty. MGI Direct Data Submission. 2018; |
All: |
1 reference(s) |
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