Apobrem1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Apobrem1(IMPC)J |
Name: |
apolipoprotein B receptor; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:6198556 |
Gene: |
Apobr Location: Chr7:126184114-126188284 bp, + strand Genetic Position: Chr7, 69.17 cM
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Alliance: |
Apobrem1(IMPC)J page
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IMPC: |
Apobr gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GTAGGACACAAACGCACTGA and GTTGCTGTGAACATCCCCTG, which resulted in a 2414 bp deletion beginning at Chromosome 7 position 126,585,381 bp and ending after 126,587,794 bp (GRCm38/mm10). This mutation deletes 2414 bp of (ENSMUSE00000349153) (exon 2) and is predicted to cause a change of amino acid sequence after residue 21 and early truncation 4 amino acids later.
(J:188991)
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Inheritance: |
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Not Specified |
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
2 reference(s) |
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