Zfp462^{Tn(pb-Act-RFP)1.090115023-HRAZhu}
Transposon induced Allele Detail

Summary

• Symbol: Zfp462^{Tn(pb-Act-RFP)1.090115023-HRAZhu}
• Name: zinc finger protein 462; transposon insertion 1.090115023-HRA, Yuan Zhuang
• MGI ID: MGI:6198748
• Gene: Zfp462 Location: Chr4:54945048-55083563 bp, + strand Genetic Position: Chr4, 29.5 cM
• Alliance: Zfp462^{Tn(pb-Act-RFP)1.090115023-HRAZhu} page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Transposon induced (Null/knockout, Reporter)
• Mutation: Transposon insertion
• Mutation details: The transposon containing an unspecified hybrid actin promoter driving expression of red fluorescent protein (RFP) flanked by piggyBac-specific left and right terminal sequences inserted at position 55,036,508 (Ensemble version 85) in intron 7. Western blot analysis confirmed the absence of protein in brains from E12.5 homozygous embryos. (J:123680, J:262219)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp462 Mutation: 336 strains or lines available

References

• Original: J:262219 Wang B, et al., Zfp462 deficiency causes anxiety-like behaviors with excessive self-grooming in mice. Genes Brain Behav. 2017 Feb;16(2):296-307
• All: 2 reference(s)