Tg(CAG-MYC,-GFP*)#Rugg
Transgene Detail

Summary

• Symbol: Tg(CAG-MYC,-GFP*)#Rugg
• Name: transgene insertion, Davide Ruggero
• MGI ID: MGI:6198762
• Synonyms: Myc^Tg
• Transgene: Tg(CAG-MYC,-GFP*)#Rugg Location: unknown
• Alliance: Tg(CAG-MYC,-GFP*)#Rugg page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(CAG-MYC,-GFP*)#Rugg expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MYC (4609)

  Bmyc	(MGI:88184)
  Myc	(MGI:97250)

• Mutation details: This transgene consists of the CAG promoter, a lox-STOP-lox element, N-terminal HA-tagged human MYC, EMCV IRES, and palmitoylated GFP. (J:261540)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:261540 Nguyen HG, et al., Development of a stress response therapy targeting aggressive prostate cancer. Sci Transl Med. 2018 May 2;10(439)
• All: 1 reference(s)