Stat1^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Stat1^m4Btlr
• Name: signal transducer and activator of transcription 1; mutation 4, Bruce Beutler
• MGI ID: MGI:6199035
• Synonyms: special
• Gene: Stat1 Location: Chr1:52158599-52201024 bp, + strand Genetic Position: Chr1, 26.81 cM
• Alliance: Stat1^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 52,139,264 (v38) on chromosome 1, or base pair 19,827 in the GenBank genomic region NC_000067. The mutation corresponds to residue 1,155 in the mRNA sequence NM_001205313 within exon 10 of 25 total exons.The mutation results in a lysine to glutamic acid substitution at amino acid 286 (K286E) in the STAT1 protein. (J:264800)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stat1 Mutation: 74 strains or lines available

References

• Original: J:264800 Choi JH, et al., Mutagenetix entry for special. MGI Direct Data Submission. 2018
• All: 1 reference(s)