Ptprcm4Btlr
Chemically induced Allele Detail
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Symbol: |
Ptprcm4Btlr |
Name: |
protein tyrosine phosphatase receptor type C; mutation 4, Bruce Beutler |
MGI ID: |
MGI:6199046 |
Synonyms: |
fuschia |
Gene: |
Ptprc Location: Chr1:137990599-138103446 bp, - strand Genetic Position: Chr1, 60.73 cM
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Alliance: |
Ptprcm4Btlr page
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Strain of Origin: |
C57BL/6J
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Project Collection: |
Beutler Mutagenetix
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Allele Type: |
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Chemically induced (ENU) (Not Specified) |
Mutation: |
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Single point mutation
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Mutation details: ENU-induced G to A transition at base pair 138,101,041 (v38) on chromosome 1, or base pair 74,716 in the GenBank genomic region NC_000067 within the donor splice site of intron 13. The effect of the mutation at the cDNA and protein levels has not been examined, but the mutation is predicted to result in skipping of the 156-nucleotide exon 13 (out of 33 total exons), resulting in an in-frame deletion of 52 amino acids (amino acids 421 to 472) of the protein (which is normally 1,293 amino acids long).
(J:264808)
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Inheritance: |
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Recessive |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ptprc Mutation: |
190 strains or lines available
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Original: |
J:264808 Choi JH, et al., Mutagenetix entry for fuchsia. MGI Direct Data Submission. 2018; |
All: |
1 reference(s) |
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