Bcl3^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Bcl3^m2Btlr
• Name: B cell leukemia/lymphoma 3; mutation 2, Bruce Beutler
• MGI ID: MGI:6199063
• Synonyms: sunrise2
• Gene: Bcl3 Location: Chr7:19542387-19556691 bp, - strand Genetic Position: Chr7, 9.95 cM
• Alliance: Bcl3^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 19,809,634 (v38) on chromosome 7, or base pair 13,134 in the GenBank genomic region NC_000073. The mutation corresponds to residue 984 in the mRNA sequence NM_033601 within exon 7 of 9 total exons. The mutation results in substitution of tyrosine 302 for a premature stop codon (Y302*) in the Bcl-3 protein. (J:264818)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl3 Mutation: 56 strains or lines available

References

• Original: J:264818 Choi JH, et al., Mutagenetix entry for sunrise2. MGI Direct Data Submission. 2018
• All: 1 reference(s)