Apbb2^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Apbb2^m2Btlr
• Name: amyloid beta precursor protein binding family B member 2; mutation 2, Bruce Beutler
• MGI ID: MGI:6199162
• Synonyms: bund
• Gene: Apbb2 Location: Chr5:66456046-66776127 bp, - strand Genetic Position: Chr5, 34.43 cM
• Alliance: Apbb2^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 66,400,255 (v38) on chromosome 5, or base pair 218,563 in the GenBank genomic region NC_000071 encoding Apbb2. The mutation corresponds to residue 1,433 in the mRNA sequence NM_001201415 within exon 6 of 16 total exons. The mutation results in a threonine (T) to serine (S) substitution at position 288 (T288S) in the APBB2 protein. (J:265072)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apbb2 Mutation: 66 strains or lines available

References

• Original: J:265072 SoRelle J, et al., Mutagenetix entry for bund. MGI Direct Data Submission. 2018
• All: 1 reference(s)