Camk2a^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Camk2a^m1Btlr
• Name: calcium/calmodulin-dependent protein kinase II alpha; mutation 1, Bruce Beutler
• MGI ID: MGI:6199624
• Synonyms: frantic
• Gene: Camk2a Location: Chr18:61058704-61121224 bp, + strand Genetic Position: Chr18, 34.41 cM
• Alliance: Camk2a^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 60,963,928 (v38) on chromosome 18, or base pair 38,352 in the GenBank genomic region NC_000084 encoding Camk2a. The mutation corresponds to residue 1,096 in the mRNA sequence NM_177407 within exon 13 of 18 total exons. The mutation results in substitution of lysine 317 to a premature stop codon (K317*) in the CaMKII protein. (J:265120)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Camk2a Mutation: 135 strains or lines available

References

• Original: J:265120 Birnbaum S, et al., Mutagenetix entry for frantic. MGI Direct Data Submission. 2018
• All: 1 reference(s)