Bcl10^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Bcl10^m1Btlr
• Name: B cell leukemia/lymphoma 10; mutation 1, Bruce Beutler
• MGI ID: MGI:6199632
• Synonyms: derek
• Gene: Bcl10 Location: Chr3:145630017-145640121 bp, + strand Genetic Position: Chr3, 71.03 cM, cytoband H3
• Alliance: Bcl10^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 145,930,587 (v38) on chromosome 3, or base pair 6,326 in the GenBank genomic region NC_000069 encoding Bcl10. The mutation corresponds to residue 436 in the mRNA sequence NM_009740 within exon 2 of 3 total exons. The mutation results in an aspartic acid to glycine substitution at position 80 (D80G) in the Bcl10 protein. (J:265122)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl10 Mutation: 16 strains or lines available

References

• Original: J:265122 Zhong X, et al., Mutagenetix entry for derek. MGI Direct Data Submission. 2018
• All: 1 reference(s)