Pax5^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Pax5^m4Btlr
• Name: paired box 5; mutation 4, Bruce Beutler
• MGI ID: MGI:6199943
• Synonyms: k2
• Gene: Pax5 Location: Chr4:44524757-44710487 bp, - strand Genetic Position: Chr4, 23.55 cM
• Alliance: Pax5^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 44,697,630 (v38) on chromosome 4, or base pair 12,811 in the GenBank genomic region NC_000070. The mutation corresponds to residue 390 in the mRNA sequence NM_008782 within exon 2 of 10 total exons. The mutation results in an aspartic acid to glycine substitution at position 35 (D35G) in the canonical variant of the PAX5 protein. (J:265140)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax5 Mutation: 37 strains or lines available

References

• Original: J:265140 Zhong X, et al., Mutagenetix entry for k2. MGI Direct Data Submission. 2018
• All: 1 reference(s)