Prkcd^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Prkcd^m2Btlr
• Name: protein kinase C, delta; mutation 2, Bruce Beutler
• MGI ID: MGI:6199966
• Synonyms: rigged2
• Gene: Prkcd Location: Chr14:30317311-30348167 bp, - strand Genetic Position: Chr14, 18.82 cM
• Alliance: Prkcd^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 30,599,743 (v38) on chromosome 14, or base pair 26,672 in the GenBank genomic region NC_000080 encoding Prkcd. The mutation corresponds to residue 1,501 in the mRNA sequence NM_001310682 within exon 14 of 17 total exons. The mutated nucleotide is indicated in red. The mutation results in a leucine to proline substitution at position 498 (L498P) in variant 1 of the PRKCD protein. (J:265146)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkcd Mutation: 54 strains or lines available

References

• Original: J:265146 Turer E, et al., Mutagenetix entry for rigged2. MGI Direct Data Submission. 2018
• All: 1 reference(s)