Ebf1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ebf1^m1Btlr
• Name: early B cell factor 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6199986
• Synonyms: crater_lake
• Gene: Ebf1 Location: Chr11:44508144-44898918 bp, + strand Genetic Position: Chr11, 26.45 cM
• Alliance: Ebf1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 44,972,908 (v38) on chromosome 11, or base pair 354,809 in the GenBank genomic region NC_000077 encoding Ebf1. The mutation corresponds to residue 1,163 in the mRNA sequence NM_001290709 within exon 11 of 16 total exons. The mutation results in substitution of lysine 362 to a premature stop codon (K362*) in variant 1 of the EBF1 protein. (J:265157)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ebf1 Mutation: 74 strains or lines available

References

• Original: J:265157 Zhong X, et al., Mutagenetix entry for crater_lake. MGI Direct Data Submission. 2018
• All: 1 reference(s)