Trpa1m1Btlr
Chemically induced Allele Detail
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Symbol: |
Trpa1m1Btlr |
Name: |
transient receptor potential cation channel, subfamily A, member 1; mutation 1, Bruce Beutler |
MGI ID: |
MGI:6199997 |
Gene: |
Trpa1 Location: Chr1:14942872-14989086 bp, - strand Genetic Position: Chr1, 4.5 cM
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Alliance: |
Trpa1m1Btlr page
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Strain of Origin: |
C57BL/6J
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Project Collection: |
Beutler Mutagenetix
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Allele Type: |
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Chemically induced (ENU) (Not Specified) |
Mutation: |
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Single point mutation
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Mutation details: ENU-induced T to C transition at base pair 14,891,303 (v38) on chromosome 1, or base pair 27,712 in the GenBank genomic region NC_000067 within the donor splice site of intron 15. The mutation is predicted to result in skipping of the 94-nucleotide exon 15 (out of 27 total exons), resulting in a frame-shifted protein product beginning after amino acid 605, and termination after the inclusion of two aberrant amino acids.
(J:262266)
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Inheritance: |
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Recessive |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Trpa1 Mutation: |
94 strains or lines available
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Original: |
J:262266 Wang Y, et al., Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors. Nat Commun. 2018 May 23;9(1):2041 |
All: |
1 reference(s) |
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