Trpa1^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Trpa1^m2Btlr
• Name: transient receptor potential cation channel, subfamily A, member 1; mutation 2, Bruce Beutler
• MGI ID: MGI:6200002
• Synonyms: petrified
• Gene: Trpa1 Location: Chr1:14942872-14989086 bp, - strand Genetic Position: Chr1, 4.5 cM
• Alliance: Trpa1^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 14,884,116 (v38) on chromosome 1, or base pair 34,899 in the GenBank genomic region NC_000067 encoding Trpa1. The mutation corresponds to residue 2,585 in the mRNA sequence NM_177781 within exon 21 of 27 total exons. The mutation results in a leucine (L) to proline (P) substitution at position 853 (L853P) in the TRPA1 protein. (J:265161)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpa1 Mutation: 92 strains or lines available

References

• Original: J:265161 Liu Q, et al., Mutagenetix entry for petrified. MGI Direct Data Submission. 2018
• All: 1 reference(s)