Klhl6^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Klhl6^m1Btlr
• Name: kelch-like 6; mutation 1, Bruce Beutler
• MGI ID: MGI:6200013
• Synonyms: cerulean
• Gene: Klhl6 Location: Chr16:19765242-19801766 bp, - strand Genetic Position: Chr16, 12.32 cM
• Alliance: Klhl6^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 19,957,218 (v38) on chromosome 16, or base pair 25,832 in the GenBank genomic region NC_000082 encoding Klhl6. The mutation corresponds to residue 635 in the mRNA sequence NM_183390 within exon 3 of 7 total exons. The mutation results in substitution of glutamine 197 for a premature stop codon (Q197*) in the KLHL6 protein. (J:265167)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klhl6 Mutation: 48 strains or lines available

References

• Original: J:265167 Choi JH, et al., Mutagenetix entry for cerulean. MGI Direct Data Submission. 2018
• All: 1 reference(s)