Klhl6^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Klhl6^m2Btlr
• Name: kelch-like 6; mutation 2, Bruce Beutler
• MGI ID: MGI:6200017
• Synonyms: blossom
• Gene: Klhl6 Location: Chr16:19765242-19801766 bp, - strand Genetic Position: Chr16, 12.32 cM
• Alliance: Klhl6^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 19,957,139 (v38) on chromosome 16, or base pair 25,911 in the GenBank genomic region NC_000082 encoding Klhl6. The mutation corresponds to residue 714 in the mRNA sequence NM_183390 within exon 3 of 7 total exons. The mutation results in an aspartic acid (D) to valine (V) substitution at position 233 (D223V) in the KLHL6 protein. (J:265168)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klhl6 Mutation: 48 strains or lines available

References

• Original: J:265168 Choi JH, et al., Mutagenetix entry for blossom. MGI Direct Data Submission. 2018
• All: 1 reference(s)