Nfkb1^M4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Nfkb1^M4Btlr
• Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; mutation 4, Bruce Beutler
• MGI ID: MGI:6200021
• Synonyms: Murgatroyd
• Gene: Nfkb1 Location: Chr3:135290416-135397308 bp, - strand Genetic Position: Chr3, 62.82 cM
• Alliance: Nfkb1^M4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to A transition at base pair 135,626,710 (v38) on chromosome 3, or base pair 65,273 in the GenBank genomic region NC_000069. The mutation corresponds to residue 785 in the mRNA sequence NM_008689 within exon 7 of 25 total exons. The mutation results in a valine to isoleucine substitution at position 95 (V95I) in the NF-B1 protein. (J:265169)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nfkb1 Mutation: 102 strains or lines available

References

• Original: J:265169 Choi JH, et al., Mutagenetix entry for Murgatroyd. MGI Direct Data Submission. 2018
• All: 1 reference(s)