Lyst^bg-11Btlr
Chemically induced Allele Detail

Summary

• Symbol: Lyst^bg-11Btlr
• Name: lysosomal trafficking regulator; beige 11 Bruce Beutler
• MGI ID: MGI:6200258
• Synonyms: charcoal
• Gene: Lyst Location: Chr13:13764982-13953388 bp, + strand Genetic Position: Chr13, 5.28 cM
• Alliance: Lyst^bg-11Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 13,696,761 (v38) on chromosome 13, or base pair 106,422 in the GenBank genomic region NC_000079 for the Lyst gene. The mutation corresponds to residue 8,263 in the mRNA sequence NM_010748 within exon 30 of 53 total exons. The mutation results in substitution of tyrosine 2,694 for a premature stop codon (Y2694*) in the Lyst protein. (J:265211)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lyst Mutation: 225 strains or lines available

References

• Original: J:265211 Prince L, et al., Mutagenetix entry for charcoal. MGI Direct Data Submission. 2018
• All: 1 reference(s)