Elmo1^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Elmo1^M1Btlr
• Name: engulfment and cell motility 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6200276
• Synonyms: Edinburg
• Gene: Elmo1 Location: Chr13:20274766-20792523 bp, + strand Genetic Position: Chr13, 7.21 cM, cytoband A3.1
• Alliance: Elmo1^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to T transversion at base pair 20,290,383 (v38) on chromosome 13, or base pair 199,877 in the GenBank genomic region NC_000079. The mutation corresponds to residue 1,314 in the mRNA sequence NM_080288 within exon 13 of 22 total exons. The mutation results in substitution of glutamic acid 326 for a premature stop codon (E326*) in the ELMO1 protein. (J:265231)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Elmo1 Mutation: 59 strains or lines available

References

• Original: J:265231 Choi JH, et al., Mutagenetix entry for Edinburg. MGI Direct Data Submission. 2018
• All: 1 reference(s)